Rabbit polyclonal primary
ZIP12 Rabbit Polyclonal Antibody (ER1706-33)
Synthetic peptide within human zip12 aa 685-691 / 691 (extracellular).
HepG2, N2A, SH-SY5Y, rat lung tissue, mouse liver tissue, mouse brain tissue, mouse eyeball tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Peptide affinity purified
bA570F3.1 antibody; FLJ30499 antibody; LIV 1 subfamily of ZIP zinc transporter 8 antibody; LIV-1 subfamily of ZIP zinc transporter 8 antibody; LZT Hs8 antibody; LZT-Hs8 antibody; LZTHs8 antibody; MGC43205 antibody; MGC51099 antibody; S39AC_HUMAN antibody; SLC39A12 antibody; Solute carrier family 39 (metal ion transporter) member 12 antibody; Solute carrier family 39 (zinc transporter) member 12 antibody; Solute carrier family 39 member 12 antibody; Zinc transporter ZIP12 antibody; ZIP 12 antibody; ZIP-12 antibody; ZIP12 antibody; Zrt and Irt like protein 12 antibody; Zrt- and Irt-like protein 12 antibody
Belongs to the ZIP transporter (TC 2.A.5) family.
Expressed in brain and eye.
Acts as a zinc-influx transporter (Potential). May be partly involved in the outbreak of schizophrenia. On the basis of sequence homology, the human SLC39A12 gene has been included as a member of a family of zinc (Zn) transporters designated as the ZRT-IRT-like proteins (current designation SLC39). ZRT-IRT-like proteins act in concert with another family of transporters, known in non-mammalian organisms as cation diffusion facilitators and in mammals as zinc transporters (ZnT), to regulate the distribution of Zn in the extra- versus intracellular milieu and within cellular compartments. Hence the ZnT maintain Zn homeostasis that is critical for the normal functioning of tissues including the CNS.