Western blot analysis of Zic2 on different lysates. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody (HA500195, 1/1,000) was used in 5% BSA at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody (HA1001) at 1:200,000 dilution was used for 1 hour at room temperature.
Lane 1: Human brain tissue lysate
Lane 2: Rat cerebellum tissue lysate
Rabbit polyclonal primary
Zic2 Rabbit Polyclonal Antibody (HA500195)
Recombinant protein within human zic2 aa 210-420.
Human brain tissue lysate, rat cerebellum tissue lysate, rat brain tissue, human skin tissue, mouse brain tissue.
HPE 5 antibody;HPE5 antibody;Odd paired homolog Drosophila antibody;Zic 2 antibody;Zic family member 2 (odd paired Drosophila homolog) antibody;Zic family member 2 antibody;ZIC2 antibody;ZIC2_HUMAN antibody;Zinc finger protein of the cerebellum 2 antibody;Zinc finger protein ZIC 2 antibody;Zinc finger protein Zic2 antibody
This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Expansion of an alanine repeat in the C-terminus of the encoded protein and other mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13.
Just like the interactions between antigens and antibodies, the higher the affinity between you and us the better.