PRODUCT CODE: R1401-10

Y14 Rabbit Polyclonal Antibody (R1401-10)

Applications

  • WB

  • ICC

  • IHC-P

REACTIVITY

  • Human

  • Mouse

  • Rat

Western blot analysis on different cell lysates using anti-Y14 rabbit polyclonal antibodies.
  • Western blot analysis on different cell lysates using anti-Y14 rabbit polyclonal antibodies.
  • ICC staining Y14 in HUVEC cells (green). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS and counterstained with DAPI in order to highlight the nucleus (blue).
  • Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti- Y14 rabbit polyclonal antibody.
  • Immunohistochemical analysis of paraffin-embedded mouse heart tissue using anti- Y14 rabbit polyclonal antibody.
Western blot analysis on different cell lysates using anti-Y14 rabbit polyclonal antibodies.

Applications

  • WB

  • ICC

  • IHC-P

REACTIVITY

  • Human

  • Mouse

  • Rat

SPECIFICATIONS

Product Type

Rabbit polyclonal primary

Product Name

Y14 Rabbit Polyclonal Antibody (R1401-10)

Immunogen

Recombinant protein

Host

Rabbit

Positive Control

Hela, MCF-7, PANC-1, HepG2, HUVEC

Conjugation

Unconjugated

Clonality

Polyclonal

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 ug/ul

PURIFICATION

Protein A purified.

MOLECULAR WEIGHT

20kDa

Isotype

IgG

APPLICATION DILUTION

  • WB

  • 1:2000-1:5000

  • IHC-P

  • 1:200

  • ICC

  • 1:200

TARGET

UNIPROT #

PROTEIN NAME

Y14

SYNONYMS

Binder of OVCA1 1 antibody; Binder of OVCA1-1 antibody; BOV 1 antibody; BOV 1A antibody; BOV 1B antibody; BOV 1C antibody; BOV-1 antibody; BOV1 antibody; BOV1A antibody; BOV1B antibody; BOV1C antibody; HSPC 114 antibody; HSPC114 antibody; MDS 014 antibody; MDS014 antibody; RBM 8 antibody; RBM 8A antibody; RBM 8B antibody; RBM8 antibody; rbm8a antibody; RBM8A_HUMAN antibody; RBM8B antibody; Ribonucleoprotein RBM 8 antibody; Ribonucleoprotein RBM 8A antibody; Ribonucleoprotein RBM8 antibody; Ribonucleoprotein RBM8A antibody; RNA binding motif protein 8 antibody; RNA binding motif protein 8A antibody; RNA binding motif protein 8B antibody; RNA binding protein 8A antibody; RNA binding protein Y14 antibody; RNA-binding motif protein 8A antibody; RNA-binding protein 8A antibody; RNA-binding protein Y14 antibody; ZNRP antibody; ZRNP 1 antibody; ZRNP1 antibody

SEQUENCE SIMILARITIES

Belongs to the RBM8A family.

TISSUE SPECIFICITY

Ubiquitous.

SUBCELLULAR LOCATION

Nucleus

FUNCTION

RNA-binding protein 8A is a protein that in humans is encoded by the RBM8A gene. This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. Two alternative start codons result in two forms of the protein, and this gene also uses multiple polyadenylation sites.