Lane 1: Hela cell lysate
Lane 2: HepG2 cell lysate
Recombinant Rabbit monoclonal primary
WNT5B Recombinant Rabbit Monoclonal Antibody [JE53-67] (ET7110-34)
Synthetic peptide within c terminal human wnt5b.
Hela cell lysate, HepG2 cell lysate, LOVO.
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A affinity purified.
Predicted band size 40 kDa.
MGC2648 antibody; Protein Wnt-5b antibody; Wingless type MMTV integration site family, member 5B antibody; WNT 5B antibody; WNT 5B protein antibody; Wnt family member 5B antibody; Wnt5b antibody; WNT5B protein antibody; WNT5B_HUMAN antibody
Belongs to the Wnt family.
Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition.
Protein Wnt-5b is a protein that in humans is encoded by the WNT5B gene. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 94% and 80% amino acid identity to the mouse Wnt5b protein and the human WNT5A protein, respectively. Alternative splicing of this gene generates 2 transcript variants.