Applications
-
WB
-
FC
REACTIVITY
-
Human
SPECIFICATIONS
Product Type
Rabbit polyclonal primary
Product Name
WDR70 Rabbit Polyclonal Antibody (ER1902-66)
Immunogen
Synthetic peptide within human wdr70 aa 1-50 / 654.
Host
Rabbit
Positive Control
Hela cell lysates, SiHa.
Conjugation
Unconjugated
Clonality
Polyclonal
PROPERTIES
Form
Liquid
Storage Condition
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 ug/ul
PURIFICATION
Peptide affinity purified.
MOLECULAR WEIGHT
Predicted band size: 73 kDa
Isotype
IgG
APPLICATION DILUTION
-
WB:1:500-1:1,000
-
FC:1:50-1:100
TARGET
UNIPROT #
PROTEIN NAME
WDR70
SYNONYMS
4833422F06Rik antibody; FLJ10233 antibody; MGC109151 antibody; RGD1309487 antibody; WD repeat containing protein 70 antibody; WD repeat domain 70 antibody; WD repeat-containing protein 70 antibody; wdr70 antibody; WDR70_HUMAN antibody
SEQUENCE SIMILARITIES
Belongs to the WD repeat GAD-1 family.
SUBCELLULAR LOCATION
Nucleus.
FUNCTION
WDR70 Antibody (C-5) is a high quality monoclonal WDR70 antibody (also designated WDR70 antibody) suitable for the detection of the WDR70 protein of mouse, rat and human origin. WDR70 Antibody (C-5) is available as both the non-conjugated anti-WDR70 antibody form, as well as multiple conjugated forms of anti-WDR70 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids, which commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms involving signal transduction, apoptosis, transcriptional regulation or cell cycle control. WD repeats serve as sites for protein-protein interaction and some seem to mediate the assembly of protein complexes. WDR70 (WD repeat-containing protein 70) is a 654 amino acid protein that contains seven WD repeats and belongs to the WD repeat GAD-1 family. WDR70 is encoded by a gene located on human chromosome 5q13.3.