Applications
-
WB
-
IHC-P
-
FC
REACTIVITY
-
Human
SPECIFICATIONS
Product Type
Recombinant Rabbit monoclonal primary
Product Name
WDR4 Recombinant Rabbit Monoclonal Antibody [JE58-28] (ET7111-37)
Immunogen
Synthetic peptide within human wdr4.
Host
Rabbit
Positive Control
K562 cell lysates, human liver carcinoma tissue, human cervical carcinoma tissue, human ovarian tumor tissue, Daudi.
Conjugation
Unconjugated
Clonality
Monoclonal
Clone Number
JE58-28
PROPERTIES
Form
Liquid
Storage Condition
Store at +4Á¾ after thawing. Aliquot store at -20Á¾. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 ug/ul
PURIFICATION
Protein A affinity purified.
MOLECULAR WEIGHT
45 kDa
Isotype
IgG
APPLICATION DILUTION
-
WB
-
1:500-1:1,000
-
IHC-P
-
1:50-1:200
-
FC
-
1:50-1:100
TARGET
UNIPROT #
PROTEIN NAME
WDR4
SYNONYMS
"OTTHUMP00000109401 antibody; OTTHUMP00000109402 antibody; TRM82 antibody; tRNA (guanine N(7) ) methyltransferase subunit WDR4 antibody; tRNA (guanine-N(7)-)-methyltransferase subunit WDR4 antibody; WD repeat containing protein 4 antibody; WD repeat protein 4 antibody; WD repeat protein domain 4 protein isoform 2 antibody; WD repeat-containing protein 4 antibody; wdr4 antibody; WDR4_HUMAN antibody"
SUBCELLULAR LOCATION
Nucleus, Chromosome.
FUNCTION
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Alternatively spliced transcript variants have been found for this gene.