WASP family, verprolin homology domain-containing protein 1 antibody;WASP family member 1 antibody;FLJ31482 antibody;homology of dictyostelium scar 1 antibody;KIAA0269 antibody;Protein WAVE-1 antibodyv Protein WAVE1 antibody;scar, Dictyostelium, homology of, 1 antibody;SCAR1 antibody;Similar to a plant extensin like protein antibody;Verprolin homology domain containing protein 1 antibody;Verprolin homology domain-containing protein 1 antibody;WAS protein family, member 1 antibody;Wasf1 antibody;WASF1_HUMAN antibody;WASL antibody;WASP family 1 antibody;WASP family protein member 1 antibody;WASP family, verprolin homology domain-containing protein antibody;WAVE antibody;WAVE1 antibody;Wiskott Aldrich syndrome protein family member 1 antibody;Wiskott-Aldrich syndrome protein family member 1 antibody
Phosphorylation at Ser-242, Tyr-256, Ser-484 and Ser-485 enhances actin polymerization activity.
Cytoplasm, cytoskeleton. Nucleus.
This gene encodes a member of the Wiskott-Aldrich syndrome (WAS) protein family. Wiskott-Aldrich syndrome proteins share similar domain structure, and associate with a variety of signaling molecules to alter the actin cytoskeleton. The encoded protein is highly expressed in neural tissues, and interacts with several proteins involved in cytoskeletal organization, including cell division control protein 42 (CDC42) and the actin-related protein-2/3 (ARP2/3) complex. The encoded protein may be involved in the formation of long actin microspikes, and in neurite extension. Regulates actin polymerization by stimulating the actin-nucleating activity of the Arp2/3 complex. Involved in mitosis and cytokinesis, via its role in the regulation of actin polymerization. Binds to HSF1/HSTF1 and forms a complex on heat shock promoter elements (HSE) that negatively regulates HSP90 expression..
Just like the interactions between antigens and antibodies, the higher the affinity between you and us the better.