PRODUCT CODE: R1307-7

VMAT1 Rabbit Polyclonal Antibody (R1307-7)

Applications

  • WB

  • ICC

REACTIVITY

  • Human

  • Rat

Western blot analysis on A549 (1) and PC12 (2) cell lysates using anti-VMAT1 rabbit polyclonal antibodies.
  • Western blot analysis on A549 (1) and PC12 (2) cell lysates using anti-VMAT1 rabbit polyclonal antibodies.
  • Immunofluorescent staining of A549 cells using anti-VMAT1 rabbit polyclonal antibody.
Western blot analysis on A549 (1) and PC12 (2) cell lysates using anti-VMAT1 rabbit polyclonal antibodies.

Applications

  • WB

  • ICC

REACTIVITY

  • Human

  • Rat

SPECIFICATIONS

Product Type

Rabbit polyclonal primary

Product Name

VMAT1 Rabbit Polyclonal Antibody (R1307-7)

Immunogen

Peptide

Host

Rabbit

Positive Control

A549, PC12

Conjugation

Unconjugated

Clonality

Polyclonal

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 ug/ul

PURIFICATION

Immunogen affinity purified

MOLECULAR WEIGHT

56 kDa

Isotype

IgG

APPLICATION DILUTION

  • WB

  • 1:500

  • ICC

  • 1:100

TARGET

UNIPROT #

PROTEIN NAME

VMAT1

SYNONYMS

4832416I10Rik antibody; Adrenal chromaffin granule amine transporter; CGAT antibody; CGAT antibody; Chromaffin granule amine transporter antibody; MGC28683 antibody; MGC37299 antibody; SLC18A1 antibody; Solute carrier family 18 (vesicular monoamine), member 1 antibody; Solute carrier family 18 member 1 antibody; VAT 1 antibody; VAT1 antibody; Vesicular amine transporter 1 antibody; VMAT 1 antibody; VMAT1_HUMAN antibody

SEQUENCE SIMILARITIES

Belongs to the major facilitator superfamily. Vesicular transporter family.

TISSUE SPECIFICITY

Highly expressed in chromaffin cells of the adrenal medulla (at protein level). Detected in peripheral sympathetic ganglia (at protein level). Found in some paracrine cells in stomach and duodenum (at protein level).

SUBCELLULAR LOCATION

Cytoplasmic vesicle membrane; Endoplasmic reticulum membrane

FUNCTION

Vesicular monoamine transporter 1 (VMAT1) also known as chromaffin granule amine transporter (CGAT) or solute carrier family 18 member 1 (SLC18A1) is a protein that in humans is encoded by the SLC18A1 gene. VMAT1 is an integral membrane protein, which is embedded in synaptic vesicles and serves to transfer monoamines, such as norepinephrine, dopamine, and serotonin, between the cytosol and synaptic vesicles.