Recombinant production enables lot-to-lot consistency and is animal-cruelty-free
Western blot analysis of Vitronectin on different lysates. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody (ET1609-39, 1/500) was used in 5% BSA at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody (HA1001) at 1:5,000 dilution was used for 1 hour at room temperature.
Lane 1: Human liver tissue lysate
Lane 2: Human serum lysate
Complement S Protein antibody;Epibolin antibody;S Protein antibody;S-protein antibody;Serum Spreading Factor antibody;Serum-spreading factor antibody;Somatomedin B antibody;Somatomedin-B antibody;V75 antibody;Vitronectin V10 subunit antibody;Vitronectin V65 subunit antibody;VN antibody;VNT antibody;VTN antibody;VTNC_HUMAN antibody
Expressed in the retina pigment epithelium (at protein level). Expressed in plasma (at protein level). Expressed in serum (at protein level).
Sulfated on tyrosine residues.; N- and O-glycosylated.; Phosphorylation on Thr-69 and Thr-76 favors cell adhesion and spreading.; It has been suggested that the active SMB domain may be permitted considerable disulfide bond heterogeneity or variability, thus two alternate disulfide patterns based on 3D structures are described with 1 disulfide bond conserved in both.; Phosphorylation sites are present in the extracellular medium.
Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway. The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.
Just like the interactions between antigens and antibodies, the higher the affinity between you and us the better.