Lane 1: Hela
Lane 2: Mouse kidney
Recombinant Rabbit monoclonal primary
VAMP8 Recombinant Rabbit Monoclonal Antibody [JF0963] (ET1702-10)
SW480, 293T, Hela, mouse brain tissue, mouse kidney tissue, human kidney tissue, mouse colon tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
EDB antibody; Endobrevin antibody; VAMP 8 antibody; VAMP-8 antibody; VAMP8 antibody; VAMP8_HUMAN antibody; Vesicle associated membrane protein 8 antibody; Vesicle-associated membrane protein 8 antibody
Belongs to the synaptobrevin family.
Lysosome membrane, Early endosome membrane, Late endosome membrane, Cell membrane.
Syntaxins were originally thought to be docking proteins, but have more recently been categorized as anchoring proteins that anchor themselves to the cytoplasmic surfaces of cellular membranes. Syntaxins bind to various proteins involved in exocytosis, including VAMPs (vesicle-associated membrane proteins), NSF (N-ethylmaleimide-sensitive factor), SNAPs (soluble NSF attachment proteins) and Synaptotagmin. Endobrevin, also designated VAMP-8 or ED, is a 100 amino acid single-pass type IV membrane protein that belongs to the synaptobrevin family. Similar in sequence to the synaptobrevins, endobrevin is abundantly expressed in kidney, moderately expressed in heart and spleen, and slightly expressed in brain, thymus and liver. Endobrevin interacts specifically with the SNAPs, most likely through an endobrevin-containing SNARE complex.