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VAChT / SLC18A3 Recombinant Rabbit Monoclonal Antibody [PSH10-50] (HA723214)

Price: Regular price $385.00

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Catalog# HA723214

Rabbit Monoclonal to VAChT / SLC18A3

Tested for

  • WB

  • IHC-Fr

  • IHC-P

Reacts with

  • Mouse

  • Rat

  • Cynomolgus monkey

  • Pig

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free

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Specifications

Product Type

Recombinant Rabbit monoclonal primary

Product Name

VAChT / SLC18A3 Recombinant Rabbit Monoclonal Antibody [PSH10-50] (HA723214)

Immunogen

Recombinant protein within n terminal mouse vacht.

Host

Rabbit

Positive Control

Mouse brain tissue, mouse striatum tissue, rat brain tissue, rat striatum tissue, Mouse brain tissue lysate, Rat brain tissue lysate.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

PSH10-50

APPLICATION DILUTION

  • WB

  • 1:1,000

  • IHC-Fr

  • 1:500

  • IHC-P

  • 1:1,000

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.

Storage Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 57 kDa

Isotype

IgG

TARGET

UNIPROT #

O35304

PROTEIN NAME

VAChT / SLC18A3

SYNONYMS

AChR antibody;MGC12716 antibody;rVAT antibody;Slc18a3 antibody;Solute carrier family 18 (vesicular acetylcholine) member 3 antibody;Solute carrier family 18 (vesicular monoamine) member 3 antibody;Solute carrier family 18 member 3 antibody;VAChT antibody;VACHT_HUMAN antibody;Vesicular acetylcholine transporter antibody

SUBCELLULAR LOCATION

Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane.

FUNCTION

The Vesicular acetylcholine transporter (VAChT) is a neurotransmitter transporter which is responsible for loading acetylcholine (ACh) into secretory organelles in neurons making acetylcholine available for secretion. It is encoded by Solute carrier family 18, member 3 (SLC18A3) gene, located within the first intron of the choline acetyltransferase gene. VAChT is able to transport ACh into vesicles by relying on an exchange between protons (H+) that were previously pumped into the vesicle diffusing out, thus acting as an antiporter. ACh molecules are then carried into the vesicle by the action of exiting protons. Acetylcholine transport utilizes a proton gradient established by a vacuolar ATPase.

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