UGP2 Mouse Monoclonal Antibody [7H1] (EM1701-76)

UNIPROT #

Q16851

PROTEIN NAME

UGP2

SYNONYMS

pHC379 antibody;UDP glucose diphosphorylase antibody;UDP glucose pyrophosphorylase 1 antibody;UDP glucose pyrophosphorylase 2 antibody;UDP glucose pyrophosphorylase antibody;UDP-glucose pyrophosphorylase antibody;UDPG antibody;UDPGP 2 antibody;UDPGP antibody;UDPGP2 antibody;UGP 1 antibody;UGP 2 antibody;UGP1 antibody;Ugp2 antibody;UGPA_HUMAN antibody;UGPase 2 antibody;UGPase antibody;UGPP 1 antibody;UGPP 2 antibody;UGPP1 antibody;UGPP2 antibody;Uridyl diphosphate glucose pyrophosphorylase 1 antibody;Uridyl diphosphate glucose pyrophosphorylase 2 antibody;UTP glucose 1 phosphate uridyltransferase antibody;UTP glucose 1 phosphate uridylyltransferase 2 antibody;UTP glucose 1 phosphate uridylyltransferase antibody;UTP--glucose-1-phosphate uridylyltransferase antibody

SEQUENCE SIMILARITIES

Belongs to the UDPGP type 1 family.

SUBCELLULAR LOCATION

Cytoplasm.

FUNCTION

UGP2 (UDP-glucose pyrophosphorylase 2), also known as UDPG, UGPP2, UDPGP2 or pHC379, is an evolutionarily conserved protein belonging to the UDPGP type 1 family of proteins. Localizing to the cytoplasm, UGP2 forms homooligomers and is believed to function as a glucosyl donor in cellular metabolic pathways. More specifically, UGP2 catalyzes the transfer of a glucose moiety from glucose-1-phosphate to UTP, producing a diphosphate and UDP-glucose. UDP-glucose is an essential precursor for the synthesis of polysaccharides; in liver and muscle, UDP-glucose is a precursor of glycogen, in liver UDP-glucose is also a precursor of UDP-glucuronate, and in lactating mammary gland UDP-glucose is converted to UDP-galactose and then to lactose.