TRIM32 Recombinant Rabbit Monoclonal Antibody [PSH08-78] (HA723030)

UNIPROT #

Q13049

PROTEIN NAME

TRIM32

SYNONYMS

72 kda Tat interacting Protein antibody;72 kDa Tat-interacting protein antibody;BBS11 antibody;E3 ubiquitin-protein ligase TRIM32 antibody;HT2A antibody;LGMD2H antibody;Limb girdle muscular dystrophy 2H (autosomal recessive) antibody;Limb girdle muscular dystrophy 2H antibody;Muscular dystrophy Hutterite type antibody;TAT interactive protein 72KD antibody;TATIP antibody;TRI32_HUMAN antibody;Trim32 antibody;Tripartite Motif Containing Protein 32 antibody;Tripartite motif-containing protein 32 antibody;Zinc finger protein HT2A antibody

SUBCELLULAR LOCATION

Cytoplasm, Mitochondrion, Endoplasmic reticulum.

FUNCTION

Tripartite motif-containing protein 32 is a protein that in humans is encoded by the TRIM32 gene. Since its discovery in 1995, TRIM32 has been shown to be implicated in a number of diverse biological pathways. The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. The protein has also been localized to the nucleus, where it interacts with the activation domain of the HIV-1 Tat protein. The Tat protein activates transcription of HIV-1 genes.