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Transmembrane protein 2 Rabbit Polyclonal Antibody (0903-5)

Price: Regular price $315.00

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Catalog# 0903-5

Rabbit Polyclonal to Transmembrane protein 2

Tested for

  • WB

  • IHC-P

React with

  • Human

  • Mouse

  • Rat

Specifications

Product Type

Rabbit polyclonal primary

Product Name

Transmembrane protein 2 Rabbit Polyclonal Antibody (0903-5)

Immunogen

Synthetic peptide within human transmembrane protein 2 aa 98-147 / 1,383.

Host

Rabbit

Positive Control

Mouse heart tissue, rat kidney tissue, human liver tissue, mouse liver tissue, mouse kidney tissue.

Conjugation

Unconjugated

Clonality

Polyclonal

APPLICATION DILUTION

  • WB

  • 1:1,000-1:2,000

  • IHC-P

  • 1:50-1:200

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Immunogen affinity purified.

Molecular Weight

Predicted band size: 154 kDa

Isotype

IgG

TARGET

UNIPROT #

Q9UHN6

PROTEIN NAME

Transmembrane protein 2

SYNONYMS

KIAA1412 antibody;TMEM 2 antibody;tmem2 antibody;TMEM2_HUMAN antibody;Transmembrane protein 2 antibody

SEQUENCE SIMILARITIES

Belongs to the CEMIP family.

TISSUE SPECIFICITY

Widely expressed.

SUBCELLULAR LOCATION

Cell membrane. Membrane.

FUNCTION

Cell surface hyaluronidase that mediates the initial cleavage of extracellular high-molecular-weight hyaluronan into intermediate-size hyaluronan of approximately 5 kDa fragments. Acts as a regulator of angiogenesis and heart morphogenesis by mediating degradation of extracellular hyaluronan, thereby regulating VEGF signaling. Is very specific to hyaluronan; not able to cleave chondroitin sulfate or dermatan sulfate.

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