Lane 1: HUVEC cell lysate
Lane 2: Mouse lung tissue lysate
Rabbit polyclonal primary
Transglutaminase 2 Rabbit Polyclonal Antibody (ER1902-28)
Recombinant protein within human transglutaminase 2 aa 317-520 / 687.
HUVEC cell lysate, mouse lung tissue lysate, HUVEC, Siha, Rat uterus tissue, Human lung cancer tissue, human placenta tissue, mouse heart tissue, Hela.
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Protein affinity purified.
ALPHA SUBUNIT antibody; C polypeptide antibody; EC 188.8.131.52 antibody; epididymis secretory protein Li 45 antibody; G alpha h antibody; G[a]h antibody; Gh CLASS G ALPHA h antibody; GNAH antibody; GNAH G PROTEIN antibody; H POLYPEPTIDE antibody; HEL-S-45 antibody; Protein glutamine gamma glutamyltransferase 2 antibody; Protein-glutamine gamma-glutamyltransferase 2 antibody; TG 2 antibody; TG(C) antibody; TG2 antibody; TGase C antibody; TGase H antibody; TGase-2 antibody; TgaseII antibody; TGC antibody; TGC GUANINE NUCLEOTIDE BINDING PROTEIN antibody; TGM2 antibody; TGM2_HUMAN antibody; Tissue transglutaminase antibody; Transglutaminase 2 antibody; Transglutaminase 2 C polypeptide antibody; Transglutaminase C antibody; Transglutaminase H antibody; Transglutaminase-2 antibody; tTG antibody; tTGas antibody
Belongs to the transglutaminase superfamily. Transglutaminase family.
Terminally differentiating mammalian epidermal cells acquire an insoluble, 10 to 20 nm thick protein deposit on the intracellular surface of the plasma membrane known as the cross-linked cell envelope (CE). The CE is a component of the epidermis that is generated through formation of disulfide bonds and g-glutamyl-lysine isodipeptide bonds, which are formed by the action of transglutaminases (TGases). TGases are intercellularly localizing, Ca2+-dependent enzymes that catalyze the formation of isopeptide bonds by transferring an amine on to glutaminyl residues, thereby cross-linking glutamine residues and lysine residues in substrate proteins. TGases influence numerous biological processes, including blood coagulation, epidermal differentiation, seminal fluid coagulation, fertilization, cell differentiation and apoptosis. Human keratinocyte transglutaminase (TGase1) is a membrane associated, 817 amino acid protein. Human tissue transglutaminase (TGase2) is an endothelial cell specific, 687 amino acid protein.