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TRADD Recombinant Rabbit Monoclonal Antibody [JE32-60] (HA722000)

Price: Regular price $385.00

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Catalog# HA722000

Rabbit Monoclonal to TRADD

Tested for

  • WB

  • IF-Cell

Reacts with

  • Human

  • Mouse

  • Rat

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free

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Specifications

Product Type

Recombinant Rabbit monoclonal primary

Product Name

TRADD Recombinant Rabbit Monoclonal Antibody [JE32-60] (HA722000)

Immunogen

Recombinant protein within human tradd aa 163-312 / 312.

Host

Rabbit

Positive Control

HeLa cell lysate, Jurkat cell lysate, RAW264.7 cell lysate, C6 cell lysate, PC-12 cell lysate, Mouse spleen tissue lysate, Rat spleen tissue lysate, HL-60 cell lysate, K-562 cell lysate, Ramos cell lysate, C2C12 cell lysate, MCF7.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

JE32-60

RRID

AB_3096695

APPLICATION DILUTION

  • WB

  • 1:1,000

  • IF-Cell

  • 1:100

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.

Storage Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 34 kDa

Isotype

IgG

TARGET

UNIPROT #

Q15628

PROTEIN NAME

TRADD

SYNONYMS

9130005N23Rik antibody;AA930854 antibody;TNFR1 associated DEATH domain protein antibody;TNFR1-associated DEATH domain protein antibody;TNFRSF1A associated via death domain antibody;TNFRSF1A-associated via death domain antibody;tradd antibody;TRADD_HUMAN antibody;Tumor necrosis factor receptor type 1 associated DEATH domain protein antibody;Tumor necrosis factor receptor type 1-associated DEATH domain protein antibody

SUBCELLULAR LOCATION

Nucleus, Cytoplasm, cytoskeleton.

FUNCTION

Tumor necrosis factor receptor type 1-associated DEATH domain protein is a protein that in humans is encoded by the TRADD gene. TRADD is an adaptor protein. The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-κB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway.

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