Positive control:
Lane 1: Daudi cell lysate
Lane 2: Human skin tissue lysate
Applications
-
WB
-
IHC-P
-
FC
REACTIVITY
-
Human
SPECIFICATIONS
Product Type
Rabbit polyclonal primary
Product Name
TMX4 Rabbit Polyclonal Antibody (ER1902-31)
Immunogen
Synthetic peptide within human tmx4 aa 300-349 / 349.
Host
Rabbit
Positive Control
Daudi cell lysate, human skin tissue lysate, human tonsil tissue, human liver carcinoma tissue, human colon carcinoma tissue, human breast carcinoma tissue, SH-SY5Y.
Conjugation
Unconjugated
Clonality
Polyclonal
PROPERTIES
Form
Liquid
Storage Condition
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 ug/ul
PURIFICATION
Peptide affinity purified
MOLECULAR WEIGHT
Predicted band size 39 kDa
Isotype
IgG
APPLICATION DILUTION
-
WB:1:500-1:1,000
-
IHC-P:1:50-1:200
-
FC:1:50-1:100
TARGET
UNIPROT #
PROTEIN NAME
TMX4
SYNONYMS
DJ971N18.2 antibody; KIAA1162 antibody; PDIA14 antibody; Protein disulfide isomerase family A 14 antibody; PSEC0095 antibody; Thioredoxin domain containing 13 antibody; Thioredoxin domain containing protein 13 antibody; Thioredoxin related transmembrane protein 4 antibody; TMX4 antibody; TXNDC 13 antibody; UNQ475/PRO938 antibody
SUBCELLULAR LOCATION
Nucleus inner membrane.
FUNCTION
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and C-terminal ASP/GLU-rich calcium binding domain. Unlike most members of this gene family, it lacks a C-terminal ER-retention sequence. The encoded protein has been shown to have reductase activity in vitro.