PRODUCT CODE: ER30606

TLR7 Rabbit Polyclonal Antibody (ER30606)

Applications

  • WB

  • IHC-P

REACTIVITY

  • Human

  • Mouse

  • Rat

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+
Western blot analysis of TLR7 on different cell lysates using anti-TLR7 antibody at 1/1000 dilution.<br />
Positive control:   <br />
Lane 1: Raji             <br />
Lane 2: Daudi <br />
Lane 3: Jurkat           <br />
Lane 4: THP-1
  • Western blot analysis of TLR7 on different cell lysates using anti-TLR7 antibody at 1/1000 dilution.<br />
Positive control:   <br />
Lane 1: Raji             <br />
Lane 2: Daudi <br />
Lane 3: Jurkat           <br />
Lane 4: THP-1
  • Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-TLR7 antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded human lung tissue using anti-TLR7 antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded mouse lung tissue using anti-TLR7 antibody. Counter stained with hematoxylin.
Western blot analysis of TLR7 on different cell lysates using anti-TLR7 antibody at 1/1000 dilution.
Positive control:
Lane 1: Raji
Lane 2: Daudi
Lane 3: Jurkat
Lane 4: THP-1

Applications

  • WB

  • IHC-P

REACTIVITY

  • Human

  • Mouse

  • Rat

SPECIFICATIONS

Product Type

Rabbit polyclonal primary

Product Name

TLR7 Rabbit Polyclonal Antibody (ER30606)

Immunogen

Peptide

Host

Rabbit

Positive Control

Raji, Daudi, Jurkat, THP-1, human tonsil tissue, human lung tissue, mouse lung tissue.

Conjugation

Unconjugated

Clonality

Polyclonal

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 ug/ul

PURIFICATION

Peptide affinity purified

MOLECULAR WEIGHT

140 kDa

Isotype

IgG

APPLICATION DILUTION

  • WB

  • 1:1,000

  • IHC-P

  • 1:200

TARGET

UNIPROT #

PROTEIN NAME

TLR7

SYNONYMS

PRO285 antibody; TLR 7 antibody; Tlr7 antibody; TLR7_HUMAN antibody; Toll like receptor 7 antibody; Toll-like receptor 7 antibody; UNQ248 antibody

SEQUENCE SIMILARITIES

Belongs to the Toll-like receptor family.

TISSUE SPECIFICITY

Detected in brain, placenta, spleen, stomach, small intestine, lung and in plasmacytoid pre-dendritic cells.

SUBCELLULAR LOCATION

Endoplasmic reticulum membrane.

FUNCTION

Members of the Toll-like receptor (TLR) family, named for the closely related Toll receptor in Drosophila, play a pivotal role in innate immune responses. TLRs recognize conserved motifs found in various pathogens and mediate defense responses. TLR7, 8 and 9 form a group of structurally related TLR family members that are localized to intracellular endosomes . TLR7 shows highest expression in lung, placenta, and spleen. TLR7 mediates responses to a class of synthetic compounds, including imidazoquinolines, guanosine-based drugs that induce anti-viral responses.