TIM 1 Recombinant Rabbit Monoclonal Antibody [JE39-41] (HA721535)
Catalog# HA721535
Rabbit Monoclonal to TIM 1
-
WB
-
Human
-
Mouse
-
Rat
Lane 1: Huh7 cell lysate
Lane 2: HepG2 cell lysate
Lane 3: NCI-H441 cell lysate
Lane 4: Jurkat cell lysate
Lane 5: NIH/3T3 cell lysate
Lane 6: RAW264.7 cell lysate
Lane 7: PC-12 cell lysate
Lysates/proteins at 20 µg/Lane.
Predicted band size: 39 kDa
Observed band size: 50 kDa
Exposure time: 3 minutes;
4-20% SDS-PAGE gel.
Proteins were transferred to a PVDF membrane and blocked with 5% NFDM/TBST for 1 hour at room temperature. The primary antibody (HA721535) at 1/1,000 dilution was used in 5% NFDM/TBST at 4℃ overnight. Goat Anti-Rabbit IgG - HRP Secondary Antibody (HA1001) at 1:100,000 dilution was used for 1 hour at room temperature.
Specifications
Product Type
Recombinant Rabbit monoclonal primary
Product Name
TIM 1 Recombinant Rabbit Monoclonal Antibody [JE39-41] (HA721535)
Immunogen
Synthetic peptide within human tim 1 aa 51-100 / 364.
Host
Rabbit
Positive Control
Huh7 cell lysate, HepG2 cell lysate, NCI-H441 cell lysate, Jurkat cell lysate, NIH/3T3 cell lysate, RAW264.7 cell lysate, PC-12 cell lysate.
Conjugation
Unconjugated
Clonality
Monoclonal
Clone Number
JE39-41
RRID
APPLICATION DILUTION
-
WB
-
1:1,000
PROPERTIES
Form
Liquid
Storage Condition
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.
Storage Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1ug/ul
Purification
Protein A affinity purified.
Molecular Weight
Predicted band size: 39 kDa
Isotype
IgG
TARGET
UNIPROT #
PROTEIN NAME
TIM 1
SYNONYMS
CD365 antibody;HAVCR 1 antibody;HAVCR antibody;HAVcr-1 antibody;Havcr1 antibody;Hepatitis A virus cellular receptor 1 antibody;Kidney injury molecule 1 antibody;KIM 1 antibody;KIM-1 antibody;T cell immunoglobin domain and mucin domain protein 1 antibody;T cell immunoglobulin mucin family member 1 antibody;T cell immunoglobulin mucin receptor 1 antibody;T-cell immunoglobulin and mucin domain-containing protein 1 antibody;T-cell membrane protein 1 antibody;TIM antibody;TIM-1 antibody;TIM1 antibody;TIMD 1 antibody;TIMD-1 antibody;TIMD1 antibody;TIMD1_HUMAN antibody
SUBCELLULAR LOCATION
Cell membrane.
FUNCTION
Phosphatidylserine receptor that plays an important functional role in regulatory B-cells homeostasis including generation, expansion and suppressor functions. As P-selectin/SELPLG ligand, plays a specialized role in activated but not naive T-cell trafficking during inflammatory responses. Controls thereby T-cell accumulation in the inflamed central nervous system (CNS) and the induction of autoimmune disease. Regulates also expression of various anti-inflammatory cytokines and co-inhibitory ligands including IL10. Acts as regulator of T-cell proliferation. May play a role in kidney injury and repair. (Microbial infection) Acts as a receptor for Ebolavirus and Marburg virus by binding exposed phosphatidyl-serine at the surface of virion membrane. Serves as a dual receptor for Ebolavirus by also interacting with envelope glycoprotein GP. (Microbial infection) Acts as a receptor for Dengue virus by binding exposed phosphatidyl-serine at the surface of virion membrane.
