Recombinant Rabbit monoclonal primary
TGN46 Recombinant Rabbit Monoclonal Antibody [JF1-024] (ET1702-56)
NIH/3T3, human kidney tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
TGN 46 antibody; TGN 51 antibody; TGN38 antibody; TGN38 homolog antibody; TGN46 antibody; TGN48 antibody; TGN51 antibody; TGOLN2 antibody; TGON2_HUMAN antibody; Trans Golgi network integral membrane protein 2 antibody; Trans golgi network protein 2 antibody; Trans Golgi network protein TGN51 antibody; Trans-Golgi network integral membrane protein 2 antibody; Trans-Golgi network protein TGN51 antibody; TTGN2 antibody
Isoform TGN46 is widely expressed. Isoform TGN51 is more abundant in fetal lung and kidney. Isoform TGN48 is barely expressed in embryonic kidney and promyelocytic cells.
Cell membrane, Golgi apparatus.
TGN38 (trans-Golgi network protein 2) is a type I integral membrane protein that constitutively cycles between the TGN and plasma membrane where it partitions nascent proteins into carrier vesicles for transport to appropriate destinations in the cell. The cytosolic domain of TGN38 interacts with AP2 Clathrin adaptor complexes via the tyrosine-containing motif (SDYQRL) to direct internalization from the plasma membrane. N- and O-linked oligosaccharide chains attach to the core TGN38 protein to produce a protein present in brain, lung and kidney.