Rabbit polyclonal primary
TESPA1 Rabbit Polyclonal Antibody (R1309-16)
Synthetic peptide within human tespa1 aa 226-270.
Human thymus, mouse thymus, human liver, A431, A172, rat brain, human lung cancer, mouse brain, mouse pancreas, HepG2.
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Peptide affinity purified.
HSPC257 antibody; K0748_HUMAN antibody; KIAA0748 antibody; Protein TESPA1 antibody; TESPA1 – thymocyte expressed, positive selection associated 1 antibody; TESPA1 antibody; thymocyte expressed, positive selection associated 1 antibody; Uncharacterized protein KIAA0748 antibody
May be phosphorylated in response to store-operated Ca(+2) entry.
TESPA1 (Thymocyte-expressed positive selection-associated protein 1) is required for the development and maturation of T-cells, its function being essential for the late stages of thymocyte development. It plays a role in T-cell antigen receptor (TCR)-mediated activation of the ERK and NFAT signaling pathways, possibly by serving as a scaffolding protein that promotes the assembly of the LAT signalosome in thymocytes.