TEAD4 Rabbit Polyclonal Antibody (ER1706-98)

UNIPROT #

Q15561

PROTEIN NAME

TEAD4

SYNONYMS

EFTR 2 antibody;EFTR2 antibody;hRTEF 1B antibody;hRTEF1B antibody;MGC9014 antibody;OTTHUMP00000238119 antibody;OTTHUMP00000238122 antibody;OTTHUMP00000238124 antibody;Related to TEF 1 antibody;Related to TEF1 antibody;Related transcription enhancer factor 1B antibody;RTEF1 antibody;TCF13L1 antibody;TEA domain family member 4 antibody;TEAD 4 antibody;TEAD-4 antibody;TEAD4 antibody;TEAD4_HUMAN antibody;TEF 3 antibody;TEF3 antibody;TEFR 1 antibody;TEFR1 antibody;Transcription factor 13 (SV40 transcriptional enhancer factor) like 1 antibody;Transcription factor 13 like 1 antibody;Transcription factor 13-like 1 antibody;Transcription factor RTEF 1 antibody;Transcription factor RTEF-1 antibody;Transcription factor RTEF1 antibody;Transcriptional enhancer factor 1 related antibody;Transcriptional enhancer factor 3 antibody;Transcriptional enhancer factor TEF 3 antibody;Transcriptional enhancer factor TEF-3 antibody;Transcriptional enhancer factor TEF3 antibody

TISSUE SPECIFICITY

Preferentially expressed in skeletal muscle. Lower levels in pancreas, placenta, and heart.

SUBCELLULAR LOCATION

Nucleus.

FUNCTION

TEF-3, also known as TEAD4 (TEA domain family member 4), RTEF1, EFTR-2, TEFR-1, TCF13L1 or hRTEF-1B, is a 427 amino acid member of the transcriptional enhancer factor (TEF) family of proteins that are characterized by the presence of a TEA DNA-binding domain. Localized to the nucleus and expressed primarily in skeletal muscle, TEF-3 functions as a transcriptional regulator by binding specifically and non-cooperatively to the M-CAT motif found in the promotors of muscle-specific genes, thereby directing their subsequent expression. TEF-3 contains one TEA DNA-binding domain and is expressed as multiple isoforms due to alternative splicing events.