Recombinant Rabbit monoclonal primary
Synapsin II Recombinant Rabbit Monoclonal Antibody [JE49-03] (ET7109-88)
Recombinant protein within human synapsin ii aa 150-300.
Rat bone marrow tissue, rat brain tissue, mouse brain tissue.
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
SYN 2 antibody; SYN II antibody; SYN IIa antibody; SYN IIb antibody; SYN2 antibody; Synapsin 2 antibody; Synapsin II isoform IIa antibody; Synapsin II isoform IIb antibody; Synapsin2 antibody; SynapsinII antibody; SYNII antibody; SYNIIa antibody; SYNIIb antibody
Belongs to the synapsin family.
Central and peripheral nervous systems.
Phosphorylation at Ser-10 dissociates synapsins from synaptic vesicles. Phosphorylation at Ser-425 by MAPK1/ERK2 and/or MAPK3/ERK1 may play a role in noradrenaline secretion by sympathetic neurons (By similarity).
Cell junction. Synapse.
This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family encodes a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal. Polymorphisms in this gene are associated with abnormal presynaptic function and related neuronal disorders, including autism, epilepsy, bipolar disorder and schizophrenia. Alternative splicing of this gene results in multiple transcript variants. The tissue inhibitor of metalloproteinase 4 gene is located within an intron of this gene and is transcribed in the opposite direction.