Lane 1: Mouse brain
Lane 2: HepG2
Recombinant Rabbit monoclonal primary
SOX10 Recombinant Rabbit Monoclonal Antibody [SN20-41] (ET1611-89)
A431, MCF-7, RH-35, HepG2, mouse brain tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
DOM antibody; DOM antibody; Dominant megacolon mouse human homolog of antibody; MGC15649 antibody; PCWH antibody; SOX 10 antibody; SOX10 antibody; SOX10_HUMAN antibody; SRY (sex determining region Y) box 10 antibody; SRY (sex determining region Y) box 10 antibody; SRY box 10 antibody; SRY box containing gene 10 antibody; SRY related HMG box gene 10 antibody; SRY related HMG box gene 10 antibody; Transcription factor SOX 10 antibody; Transcription factor SOX-10 antibody; WS2E antibody; WS4 antibody; WS4C antibody
Expressed in fetal brain and in adult brain, heart, small intestine and colon.
Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.