Lane 1: SW480 cell lysate
Lane 2: A549 cell lysate
Lane 3: HepG2 cell lysate
Lane 4: SKOV-3 cell lysate
Lane 5: 293 cell lysate
Lane 6: HCT116 cell lysate
Recombinant Rabbit monoclonal primary
SLC31A1 Recombinant Rabbit Monoclonal Antibody [JE56-93] (HA720005)
Synthetic peptide within n-terminal human slc31a1.
SW480 cell lysate, A549 cell lysate, HepG2 cell lysate, SKOV-3 cell lysate, 293 cell lysate, HCT116 cell lysate, rat testis tissue lysate, mouse spleen lysate, SW620.
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A affinity purified.
Predicted band size: 21 kDa.
Copper transport 1 homolog antibody; Copper transporter 1 antibody; COPT1 antibody; COPT1_HUMAN antibody; CTR1 antibody; hCTR1 antibody; High affinity copper uptake protein 1 antibody; SLC31A1 antibody; solute carrier family 31 (copper tansporters) member 1 antibody; Solute carrier family 31 member 1 antibody
High affinity copper uptake protein 1 (Ctr1) is a protein that in humans is encoded by the SLC31A1 gene. Copper is an element essential for life, but excessive copper can be toxic or even lethal to the cell. Therefore, cells have developed sophisticated ways to maintain a critical copper balance, with the intake, export, and intracellular compartmentalization or buffering of copper strictly regulated. The 2 related genes ATP7A (MIM 300011) and ATP7B (MIM 606882), responsible for the human diseases Menkes syndrome (MIM 309400) and Wilson disease (MIM 277900), respectively, are involved in copper export. In S. cerevisiae, the copper uptake genes CTR1, CTR2, and CTR3 have been identified, and in human the CTR1 and CTR2 (MIM 603088) genes have been identified.