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Slc12a5 / KCC2 Recombinant Mouse Monoclonal Antibody [PSH13-20] (HA601433)

Price: Regular price $350.00

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Catalog# HA601433

Mouse Monoclonal to Slc12a5 / KCC2

Tested for

  • IHC-Fr

  • WB

Reacts with

  • Mouse

  • Rat

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free

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Specifications

Product Type

Recombinant Mouse monoclonal primary

Product Name

Slc12a5 / KCC2 Recombinant Mouse Monoclonal Antibody [PSH13-20] (HA601433)

Immunogen

Recombinant protein within rat slc12a5 / kcc2 aa 932-1043.

Host

Mouse

Positive Control

Mouse hippocampus tissue lysate, Mouse brain tissue lysate, Rat brain tissue lysate.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

PSH13-20

APPLICATION DILUTION

  • IHC-Fr

  • 1:500

  • WB

  • 1:5,000

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.

Storage Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 126 kDa

Isotype

IgG1

TARGET

UNIPROT #

Q91V14

PROTEIN NAME

Slc12a5 / KCC2

SYNONYMS

Electroneutral potassium chloride cotransporter 2 antibody;Electroneutral potassium-chloride cotransporter 2 antibody;Erythroid K Cl cotransporter 2 antibody;Furosemide sensitive K Cl cotransporter antibody;hKCC2 antibody;K-Cl cotransporter 2 antibody;KCC 2 antibody;KCC2 antibody;KIAA1176 antibody;Neuronal K Cl cotransporter antibody;Neuronal K-Cl cotransporter antibody;Potassium Chloride Cotransporter antibody;Potassium chloride transporter 5 antibody;rKCC2 antibody;S12A5 antibody;S12A5_HUMAN antibody;SLC12A5 antibody;Solute carrier family 12 (potassium chloride transporter) member 5 antibody;Solute carrier family 12 member 5 antibody

SUBCELLULAR LOCATION

Cell membrane, Cell projection, dendrite.

FUNCTION

Mediates electroneutral potassium-chloride cotransport in mature neurons and is required for neuronal Cl- homeostasis. As major extruder of intracellular chloride, it establishes the low neuronal Cl- levels required for chloride influx after binding of GABA-A and glycine to their receptors, with subsequent hyperpolarization and neuronal inhibition (By similarity). Involved in the regulation of dendritic spine formation and maturation.

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