Recombinant Rabbit monoclonal primary
Skp1 Recombinant Rabbit Monoclonal Antibody [JM27-37] (ET1705-43)
PC-12, Hela, SH-SY5Y.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
Cyclin A/CDK2 associated p19 antibody; Cyclin A/CDK2 associated protein p19 antibody; Cyclin-A/CDK2-associated protein p19 antibody; EMC19 antibody; MGC34403 antibody; OCP 2 antibody; OCP II antibody; OCP II protein antibody; OCP-2 antibody; OCP-II antibody; OCP2 antibody; OCPII antibody; Organ of Corti protein 2 antibody; Organ of Corti protein II antibody; OTTHUMP00000159379 antibody; OTTHUMP00000159380 antibody; OTTHUMP00000228275 antibody; OTTHUMP00000228276 antibody; OTTHUMP00000228278 antibody; OTTHUMP00000228279 antibody; OTTHUMP00000228281 antibody; p19A antibody; p19skp1 antibody; RNA polymerase II elongation factor like protein antibody; RNA polymerase II elongation factor like protein OCP2 antibody; RNA polymerase II elongation factor-like protein antibody; S phase kinase associated protein 1 antibody; S phase kinase associated protein 1A antibody; S phase kinase associated protein 1A p19A antibody; S-phase kinase-associated protein 1 antibody; SIII antibody; Skp 1 antibody; SKP 1A antibody; skp1 antibody; SKP1_HUMAN antibody; SKP1A antibody; TCEB1L antibody; Transcription Elongation Factor B 1 like antibody; Transcription elongation factor B antibody; Transcription elongation factor B SIII polypeptide 1 like antibody
Belongs to the SKP1 family.
Undergoes autophagy-mediated degradation in the liver in a time-dependent manner.
Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. SCF(BTRC) mediates the ubiquitination of NFKBIA at 'Lys-21' and 'Lys-22'; the degradation frees the associated NFKB1-RELA dimer to translocate into the nucleus and to activate transcription. SCF(Cyclin F) directs ubiquitination of CP110.