Sigma1-receptor Rabbit Polyclonal Antibody (HA500511)
Catalog# HA500511
Rabbit Polyclonal to Sigma1-receptor
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WB
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IHC-P
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Human
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Mouse
Positive control:
Lane 1: 293T cell lysate
Lane 2: HepG2 cell lysate
Lane 3: Mouse liver tissue lysate
Specifications
Product Type
Rabbit polyclonal primary
Product Name
Sigma1-receptor Rabbit Polyclonal Antibody (HA500511)
Immunogen
Recombinant protein within human sigma1-receptor aa 74-223.
Host
Rabbit
Positive Control
293T cell lysate, HepG2 cell lysate, mouse liver tissue lysate, human liver tissue, human placenta tissue, mouse brain tissue.
Conjugation
Unconjugated
Clonality
Polyclonal
RRID
APPLICATION DILUTION
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WB
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1:500
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IHC-P
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1:600-1:1,000
PROPERTIES
Form
Liquid
Storage Condition
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.
Storage Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1ug/ul
Purification
Immunogen affinity purified.
Molecular Weight
Predicted band size: 25 kDa.
Isotype
IgG
TARGET
UNIPROT #
PROTEIN NAME
Sigma1-receptor
SYNONYMS
Aging associated gene 8 protein antibody;Aging-associated gene 8 protein antibody;AL024364 antibody;hSigmaR1 antibody;mSigmaR1 antibody;opioid receptor, sigma 1 antibody;opioid receptor, sigma 1 isoform 1 antibody;RP23 167I12.6 antibody;SGMR1_HUMAN antibody;SIG 1R antibody;SIG-1R antibody;Sigma 1-type opioid receptor antibody;Sigma non-opioid intracellular receptor 1 antibody;sigma1 receptor antibody;Sigma1-receptor antibody;Sigma1R antibody;Sigmar1 antibody;SR BP antibody;SR-BP antibody;SR31747 binding protein antibody;SR31747-binding protein antibody;SRBP antibody
SUBCELLULAR LOCATION
Cell junction, Cell membrane, Cell projection, Cytoplasmic vesicle, Endoplasmic reticulum, Lipid droplet, Membrane, Nucleus, Postsynaptic cell membrane, Synapse.
FUNCTION
This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.
CITATIONS
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Chloroquine Intervenes Nephrotoxicity of Nilotinib through Deubiquitinase USP13‐Mediated Stabilization of Bcl‐XL
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WB
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Human
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Citation
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