Positive control:
Lane 1: HepG2 cell lysate
Lane 2: HL-60 cell lysate
Applications
-
WB
-
IHC-P
REACTIVITY
-
Human
-
Mouse
SPECIFICATIONS
Product Type
Rabbit polyclonal primary
Product Name
SERPING1 Rabbit Polyclonal Antibody (HA500008)
Immunogen
Recombinant protein within human serping1 aa 145-403.
Host
Rabbit
Positive Control
HepG2 cell lysate, HL-60 cell lysate, human liver tissue, human placenta tissue, mouse liver tissue.
Conjugation
Unconjugated
Clonality
Polyclonal
PROPERTIES
Form
Liquid
Storage Condition
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 ug/ul
PURIFICATION
Protein affinity purified.
MOLECULAR WEIGHT
55 kDa
Isotype
IgG
APPLICATION DILUTION
-
WB
-
1:500-1:1,000
-
IHC-P
-
1:200-1:1000
TARGET
UNIPROT #
PROTEIN NAME
SERPING1
SYNONYMS
C1 esterase inhibitor antibody; C1 Inh antibody; C1 inhibiting factor antibody; C1 inhibitor antibody; C1-inhibiting factor antibody; C1IN antibody; C1Inh antibody; C1NH antibody; complement component 1 inhibitor antibody; esterase inhibitor antibody; HAE1 antibody; HAE2 antibody; IC1_HUMAN antibody; Plasma protease C1 inhibitor antibody; Serine (or cysteine) proteinase inhibitor clade G member 1 antibody; serine/cysteine proteinase inhibitor clade G member 1 antibody; Serpin G1 antibody; serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 antibody; SERPING1 antibody
SUBCELLULAR LOCATION
Secreted.
FUNCTION
Activation of the C1 complex is under control of the C1-inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein.