Western blot analysis of SeL1L on Zebrafish lysate. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody was used at a 1:500 dilution in 5% BSA at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody (HA1001) at 1:5,000 dilution was used for 1 hour at room temperature.
Rabbit polyclonal primary
SEL1L Rabbit Polyclonal Antibody (ER1803-69)
Recombinant protein within zebrafish sel1l aa 109-281 / 776.
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
IBD2 antibody;PRO1063 antibody;Protein sel-1 homolog 1 antibody;SE1L1_HUMAN antibody;Sel 1 like protein antibody;Sel 1 suppressor of lin 12 like antibody;Sel-1L antibody;SEL1 LIKE antibody;Sel1l antibody;SEL1LIKE antibody;Suppressor of lin-12-like protein 1 antibody;TSA305 antibody;UNQ128 antibody;UNQ128/PRO1063 antibody
Protein sel-1 homolog 1 is a protein that in humans is encoded by the SEL1L gene. May play a role in Notch signaling. May be involved in the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. In mammals, the most well-characterized ERAD machinery is the highly conserved complex of suppressor-enhancer of lin-12–like and hydroxymethylglutaryl-CoA reductase degradation protein 1 (SEL1L-HRD1), which consists of the E3 ubiquitin ligase HRD1 and its adaptor protein SEL1Lc.The Sel1L-deficient experimental model of central diabetes insipidus is unlikely to be observed in humans, as Sel1L loss is embryonically lethal. Three-week-old mice with Sel1L deficiency specifically in AVP neurons (Sel1LAVP mice) lacked AVP-positive transport vesicles in axons, a phenotype that explains the development of the central diabetes insipidus phenotype in these mice.
Just like the interactions between antigens and antibodies, the higher the affinity between you and us the better.