Lane 1: mouse liver tissue lysate
Lane 2: human liver tissue lysate
Recombinant Rabbit monoclonal primary
Scavenging Receptor SR-BI Recombinant Rabbit Monoclonal Antibody [SR37-06] (ET1602-32)
Synthetic peptide within human srb1 aa 81-130 / 552.
Mouse liver tissue lysate, human liver tissue lysate, CRC, PC-12, human liver tissue, human spleen tissue, mouse liver tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A affinity purified.
Scavenging Receptor SR-BI
CD36 and LIMPII analogous 1 antibody; CD36 antibody; CD36 Antigen like 1 antibody; CD36 antigen-like 1 antibody; CD36L1 antibody; CLA 1 antibody; CLA-1 antibody; CLA1 antibody; Collagen type I receptor antibody; HDLQTL6 antibody; MGC138242 antibody; SCARB1 antibody; Scavebger Receptor Class B Member 1 antibody; Scavenger receptor class B member 1 antibody; Scavenger Receptor Class B Type 1 antibody; SCRB1_HUMAN antibody; SR BI antibody; SR-BI antibody; SRB1 antibody; SRBI antibody; Thrombospondin receptor like 1 antibody; thrombospondin receptor-like 1 antibody
Belongs to the CD36 family.
N-glycosylated.; The six cysteines of the extracellular domain are all involved in intramolecular disulfide bonds.
Cell membrane, caveola.
The macrophage class A scavenger receptors (SR-A) type I and II mediate the uptake of modified low density lipoprotein (LDL), while the scavenger receptor class B type 1 (SR-B1) mediates the selective uptake of cholesterol and cholesterol esters (CE) from HDLs into cells. SREC, Ox-LDL-R1, SR-A and SR-B1 may all be involved in the early development of atherosclerosis. SR-B1, an integral membrane protein, acts as a receptor for various ligands, including apoptotic cells, cholesterol ester, phospholipids, lipoproteins and phosphatidyl-serine. SR-B1, which may be involved in phagocytosis of apoptotic cells, enables the movement of cholesterol between the cell surface and extracellular donors and acceptors. Although it is widely expressed, SR-B1 localizes primarily to cholesterol and sphingomyelin-enriched domains within the plasma membrane, called caveolae.