SAP97 Rabbit Polyclonal Antibody (ER2001-07)

UNIPROT #

Q12959

PROTEIN NAME

SAP97

SYNONYMS

Discs large homolog 1 antibody;discs large, Drosophila, homolog of, 1 antibody;discs, large homolog 1 (Drosophila) antibody;Disks large homolog 1 antibody;dJ1061C18.1.1 antibody;DKFZp761P0818 antibody;DKFZp781B0426 antibody;DLG 1 antibody;DLG1 antibody;DLG1_HUMAN antibody;DLGH 1 antibody;DLGH1 antibody;hDlg antibody;Presynaptic protein SAP97 antibody;SAP 97 antibody;SAP-97 antibody;SAP97 antibody;Synapse associated protein 97 antibody;Synapse-associated protein 97 antibody

SUBCELLULAR LOCATION

Cell junction, Cell membrane, Cytoplasm, Endoplasmic reticulum, Membrane, Synapse.

FUNCTION

Essential multidomain scaffolding protein required for normal development (By similarity). Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells. May play a role in adherens junction assembly, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Regulates the excitability of cardiac myocytes by modulating the functional expression of Kv4 channels. Functional regulator of Kv1.5 channel.This gene encodes a multi-domain scaffolding protein that is required for normal development. This protein may have a role in septate junction formation, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene, but the full-length nature of some of the variants is not known.