S100A8+S100A9 Recombinant Rabbit Multiclonal Antibody (IRS196RB)

UNIPROT #

P27005

PROTEIN NAME

S100A8+S100A9

SYNONYMS

Calgranulin-A antibody;Calprotectin L1L subunit antibody;CFAG antibody;Cystic fibrosis antigen antibody;Leukocyte L1 complex light chain antibody;Migration inhibitory factor-related protein 8 antibody;MRP-8 antibody;N-terminally processed antibody;p8 antibody;Protein S100-A8 antibody;S100 calcium-binding protein A8 antibody;S100A8 antibody;S10A8_HUMAN antibody;Urinary stone protein band A antibody;Leukocyte L1 complex heavy chain antibody;60B8AG antibody;CAGB antibody;Calgranulin B antibody;Calgranulin-B antibody;Calprotectin L1H subunit antibody;CFAG antibody;CGLB antibody;Cystic fibrosis antigen B antibody;L1AG antibody;Leukocyte L1 complex heavy chain antibody;LIAG antibody;MAC387 antibody;MIF antibody;Migration inhibitory factor related protein 14 antibody;Migration inhibitory factor-related protein 14 antibody;MRP 14 antibody;MRP-14 antibody;MRP14 antibody;Myeloid-related protein 14 antibody;NIF antibody;OTTHUMP00000015331 antibody;p14 antibody;Protein S100-A9 antibody;S100 A9 antibody;S100 calcium binding protein A9 antibody;S100 calcium binding protein A9 calgranulin B antibody;S100 calcium-binding protein A9 antibody;S100A9 antibody;S10A9_HUMAN antibody

SUBCELLULAR LOCATION

Secreted, Cytoplasm, cytoskeleton, Cell membrane

FUNCTION

S100 calcium-binding protein A8 (S100A8) is a protein that in humans is encoded by the S100A8 gene.[5] It is also known as calgranulin A. S100 calcium-binding protein A9 (S100A9) also known as migration inhibitory factor-related protein 14 (MRP14) or calgranulin B is a protein that in humans is encoded by the S100A9 gene. The proteins S100A8 and S100A9 form a heterodimer called calprotectin. The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis [5] and post COVID-19 condition.