PRODUCT CODE: ET1702-38

S100A10 Recombinant Rabbit Monoclonal Antibody [JF0987] (ET1702-38)

  • Recombinant

Applications

  • WB

  • IHC-P

REACTIVITY

  • Human

  • Mouse

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Western blot analysis of S100A10 on human lung lysates using anti-S100A10 antibody at 1/1,000 dilution.
  • Western blot analysis of S100A10 on human lung lysates using anti-S100A10 antibody at 1/1,000 dilution.
  • Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-S100A10 antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-S100A10 antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded human gastric carcinoma tissue using anti-S100A10 antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-S100A10 antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-S100A10 antibody. Counter stained with hematoxylin.
Western blot analysis of S100A10 on human lung lysates using anti-S100A10 antibody at 1/1,000 dilution.

Applications

  • WB

  • IHC-P

REACTIVITY

  • Human

  • Mouse

SPECIFICATIONS

Product Type

Recombinant Rabbit monoclonal primary

Product Name

S100A10 Recombinant Rabbit Monoclonal Antibody [JF0987] (ET1702-38)

Immunogen

Recombinant protein

Host

Rabbit

Positive Control

Human lung tissue, human colon cancer tissue, human kidney tissue, human gastric carcinoma tissue, mouse colon tissue, mouse kidney tissue.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

JF0987

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 ug/ul

PURIFICATION

Protein A purified.

MOLECULAR WEIGHT

11 kDa

Isotype

IgG

APPLICATION DILUTION

  • WB

  • 1:1,000-1:2,000

  • IHC-P

  • 1:50-1:200

TARGET

UNIPROT #

PROTEIN NAME

S100A10

SYNONYMS

42C antibody; AA409961 antibody; AL024248 antibody; Annexin II ligand antibody; Annexin II ligand, calpactin I, light polypeptide antibody; Annexin II tetramer (AIIt) p11 subunit antibody; Annexin II, light chain antibody; ANX2L antibody; ANX2LG antibody; Ca[1] antibody; CAL12 antibody; CAL1L antibody; Calpactin I light chain antibody; Calpactin I, p11 subunit antibody; Calpactin-1 light chain antibody; Cellular ligand of annexin II antibody; CLP11 antibody; GP11 antibody; MGC111133 antibody; Nerve growth factor-induced protein 42C antibody; OTTHUMP00000015269 antibody; OTTHUMP00000015270 antibody; p10 antibody; p10 protein antibody; p11 antibody; Protein S100 A10 antibody; Protein S100-A10 antibody; S100 calcium binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11)) antibody; S100 calcium binding protein A10 (calpactin) antibody; S100 calcium binding protein A10 antibody; S100 calcium-binding protein A10 antibody; S100a10 antibody; S10AA_HUMAN antibody

SEQUENCE SIMILARITIES

Belongs to the S-100 family.

SUBCELLULAR LOCATION

Extracellular exosome.

FUNCTION

The S-100 family of calcium-activated proteins interact with a range of target proteins to modulate biological signaling pathways. Numerous cancer cell lines overexpress the plasminogen receptor S-100A10 on the extracellular cell surface, where it forms a heterotetrameric complex with Annexin II, though this association is not required for plasma membrane localization or binding and activation of plasminogen. Additionally, S-100A10 acts as a cellular chaperone for hepatitis B (Hep B) virus polymerase. Hep B virus polymerase normally localizes to the cytoplasm only, though in the presence of S-100A10 a portion relocates to the nucleus, implying a role for S-100A10 and intracellular calcium in the process of viral replication.