Recombinant Rabbit monoclonal primary
S100A10 Recombinant Rabbit Monoclonal Antibody [JF0987] (ET1702-38)
Human lung tissue, human colon cancer tissue, human kidney tissue, human gastric carcinoma tissue, mouse colon tissue, mouse kidney tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
42C antibody; AA409961 antibody; AL024248 antibody; Annexin II ligand antibody; Annexin II ligand, calpactin I, light polypeptide antibody; Annexin II tetramer (AIIt) p11 subunit antibody; Annexin II, light chain antibody; ANX2L antibody; ANX2LG antibody; Ca antibody; CAL12 antibody; CAL1L antibody; Calpactin I light chain antibody; Calpactin I, p11 subunit antibody; Calpactin-1 light chain antibody; Cellular ligand of annexin II antibody; CLP11 antibody; GP11 antibody; MGC111133 antibody; Nerve growth factor-induced protein 42C antibody; OTTHUMP00000015269 antibody; OTTHUMP00000015270 antibody; p10 antibody; p10 protein antibody; p11 antibody; Protein S100 A10 antibody; Protein S100-A10 antibody; S100 calcium binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11)) antibody; S100 calcium binding protein A10 (calpactin) antibody; S100 calcium binding protein A10 antibody; S100 calcium-binding protein A10 antibody; S100a10 antibody; S10AA_HUMAN antibody
Belongs to the S-100 family.
The S-100 family of calcium-activated proteins interact with a range of target proteins to modulate biological signaling pathways. Numerous cancer cell lines overexpress the plasminogen receptor S-100A10 on the extracellular cell surface, where it forms a heterotetrameric complex with Annexin II, though this association is not required for plasma membrane localization or binding and activation of plasminogen. Additionally, S-100A10 acts as a cellular chaperone for hepatitis B (Hep B) virus polymerase. Hep B virus polymerase normally localizes to the cytoplasm only, though in the presence of S-100A10 a portion relocates to the nucleus, implying a role for S-100A10 and intracellular calcium in the process of viral replication.