RGS6 Rabbit Polyclonal Antibody (HA500233)

UNIPROT #

P49758

PROTEIN NAME

RGS6

SYNONYMS

FLJ43552 antibody;G protein signaling 6 regulator antibody;GAP antibody;GTPase activating protein antibody;MGC142132 antibody;Regulator of G protein signaling 6 antibody;Regulator of G protein signalling 6 antibody;Regulator of G-protein signaling 6 antibody;RGS 6 antibody;RGS6 antibody;RGS6_HUMAN antibody;S914 antibody

SUBCELLULAR LOCATION

Nucleus, Cytoplasm, Cytosol, Cell membrane, Membrane.

FUNCTION

This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Many alternatively spliced transcript variants encoding different isoforms with long or short N-terminal domains, complete or incomplete GGL domains, and distinct C-terminal domains, have been described for this gene, however, the full-length nature of some of these variants is not known.