RBPMS Rabbit Polyclonal Antibody (ER1901-43)

UNIPROT #

Q93062

PROTEIN NAME

RBPMS

SYNONYMS

FLJ32971 antibody;Heart and RRM expressed sequence antibody;Hermes antibody;RBP MS antibody;RBP-MS antibody;Rbpms antibody;RBPMS_HUMAN antibody;RNA binding protein gene with multiple splicing antibody;RNA-binding protein with multiple splicing antibody

TISSUE SPECIFICITY

Ubiquitously expressed, at various levels depending on the isoform and the tissue.

SUBCELLULAR LOCATION

Cytoplasm, Nucleus.

FUNCTION

RNA-binding protein with multiple splicing is a protein that in humans is encoded by the RBPMS gene. This gene encodes a member of the RRM family of RNA-binding proteins. The RRM domain is between 80-100 amino acids in length and family members contain one to four copies of the domain. The RRM domain consists of two short stretches of conserved sequence called RNP1 and RNP2, as well as a few highly conserved hydrophobic residues. The protein encoded by this gene has a single, putative RRM domain in its N-terminus. Alternative splicing results in multiple transcript variants encoding different isoforms. It is uniquely expressed in retinal ganglion cells in the mammalian retina, for reasons unknown. RBPMS has been shown to interact with SMUG1.