Rabbit polyclonal primary
Prolactin/PRL Rabbit Polyclonal Antibody (ER1803-72)
Recombinant protein within human prolactin/prl aa 50-200.
A549, SH-SY-5Y, SiHa, rat pituitary tissue, rat brain tissue, mouse brain tissue.
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Protein affinity purified.
Decidual prolactin antibody; GHA1 antibody; Growth hormone A1 antibody; Lactogenic hormone antibody; Luteotropic hormone antibody; Mammotropin antibody; PRL antibody; Prolactin antibody; Prolactin precursor antibody
Belongs to the somatotropin/prolactin family.
Prolactin (PRL), also known as luteotropic hormone or luteotropin, is a protein that is best known for its role in enabling mammals, usually females, to produce milk. It is influential in over 300 separate processes in various vertebrates, including humans. Prolactin is secreted from the pituitary gland in response to eating, mating, estrogen treatment, ovulation and nursing. Prolactin is secreted in pulses in between these events. Prolactin plays an essential role in metabolism, regulation of the immune system and pancreatic development. Prolactin also acts in a cytokine-like manner and as an important regulator of the immune system. It has important cell cycle-related functions as a growth-, differentiating- and anti-apoptotic factor. As a growth factor, binding to cytokine-like receptors, it influences hematopoiesis, angiogenesis and is involved in the regulation of blood clotting through several pathways. The hormone acts in endocrine, autocrine and paracrine manner through the prolactin receptor and a large number of cytokine receptors. Pituitary prolactin secretion is regulated by endocrine neurons in the hypothalamus.