Skip to content

Contact

(857) 353-6600

orders@huabio.com

PRDM14 Rabbit Polyclonal Antibody (R1310-4)

Price: Regular price $315.00

Unit price per 

Volume

Bulk Order Quote   |   Customization Request

Catalog# R1310-4

Rabbit Polyclonal to PRDM14

Tested for

  • WB

  • IF-Cell

  • IHC-P

Reacts with

  • Human

Safety datasheet

Select your chosen country/region

COA DOWNLOAD

Specifications

Product Type

Rabbit polyclonal primary

Product Name

PRDM14 Rabbit Polyclonal Antibody (R1310-4)

Immunogen

Recombinant protein within human prdm14 aa 1-250 / 571.

Host

Rabbit

Positive Control

Human embryonic stem cells, human lung, MCF-7

Conjugation

Unconjugated

Clonality

Polyclonal

RRID

AB_3073253

APPLICATION DILUTION

  • WB

  • 1:500-1:1,000

  • IF-Cell:1:100

  • IHC-P

  • 1:100

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Immunogen affinity purified.

Molecular Weight

~64kDa

Isotype

IgG

TARGET

UNIPROT #

Q9GZV8

PROTEIN NAME

PRDM14

SYNONYMS

MGC59730 antibody;PFM 11 antibody;PFM11 antibody;PR domain containing 14 antibody;PR domain zinc finger protein 14 antibody;PR domain-containing protein 14 antibody;PRD14_HUMAN antibody;PRDM 14 antibody;PRDM14 antibody

SEQUENCE SIMILARITIES

Belongs to the class V-like SAM-binding methyltransferase superfamily.

TISSUE SPECIFICITY

Expressed in embryonic stem cells. Tends to be overexpressed in breast cancer (at protein level).

SUBCELLULAR LOCATION

Nucleus

FUNCTION

PR domain zinc finger protein 14 is a transcription factor that has both positive and negative roles on transcription. It is expressed in embryonic stem cells and tends to be overexpressed in breast cancer. PRDM14 is required for the maintenance of emryonic stem cell identity and the reacquisition of pluripotency in somatic cells. It may play an essential role in germ cell development at 2 levels: the reacquisition of potential pluripotency, including SOX2 up-regulation, and successful epigenetic reprogramming, characterized by EHMT1 repression. PRDM14 directly up-regulates the expression of pluripotency gene POU5F1 through its proximal enhancer.

Close (esc)

Popup

Use this popup to embed a mailing list sign up form. Alternatively use it as a simple call to action with a link to a product or a page.

Age verification

By clicking enter you are verifying that you are old enough to consume alcohol.

Enter

Search

Main menu

Your cart is currently empty.
Shop now