Skip to content

Contact

(857) 353-6600

orders@huabio.com

PRDC Rabbit Polyclonal Antibody (HA500225)

Price: Regular price $315.00

Unit price per 

Volume

Bulk Order Quote   |   Customization Request

Catalog# HA500225

Rabbit Polyclonal to PRDC

Tested for

  • WB

  • FC

Reacts with

  • Human

Safety datasheet

Select your chosen country/region

COA DOWNLOAD

Specifications

Product Type

Rabbit polyclonal primary

Product Name

PRDC Rabbit Polyclonal Antibody (HA500225)

Immunogen

Synthetic peptide within human prdc aa 50-100.

Host

Rabbit

Positive Control

CAL62 cell lysates, SH-SY5Y.

Conjugation

Unconjugated

Clonality

Polyclonal

RRID

AB_3071322

APPLICATION DILUTION

  • WB

  • 1:500-1:1,000

  • FC

  • 1:200-1:500

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.

Storage Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Immunogen affinity purified.

Molecular Weight

Predicted band size: 19 kDa.

Isotype

IgG

TARGET

UNIPROT #

Q9H772

PROTEIN NAME

PRDC

SYNONYMS

BMP antagonist 2 antibody;CKTSF1B2 antibody;Cysteine knot superfamily 1 antibody;Cysteine knot superfamily 1 BMP antagonist 2 antibody;DAN domain family member 3 antibody;DAND 3 antibody;DAND3 antibody;GREM 2 antibody;Grem2 antibody;GREM2_HUMAN antibody;Gremlin 2 antibody;Gremlin 2 cysteine knot superfamily homolog antibody;Gremlin-2 antibody;Gremlin2 antibody;PRDC antibody;Protein related to DAN and cerberus antibody

SUBCELLULAR LOCATION

Secreted.

FUNCTION

PRDC (protein related to DAN and Cerberus) is a secreted cysteine knot-containing BMP antagonist belonging to the Cerberus/DAN (CAN) family. Mammalian CAN family members, including Gremlin, Dan, Cerberus, COCO, SOST, and USAG-1, have the conserved 6 cysteine residues that form a cysteine knot, and two additional cysteine residues located in the loops of the cysteine knot, which form an additional intrasubunit disulfide bond. PRDC acts as a specific BMP antagonist, binding to and blocking signaling induced by BMP-2 or -4, but not Activin or TGF-beta. Thus, PRDC expression in the ovary could be involved in follicular development by antagonizing the inhibitory effects of BMPs on FSH stimulation of progesterone

Close (esc)

Popup

Use this popup to embed a mailing list sign up form. Alternatively use it as a simple call to action with a link to a product or a page.

Age verification

By clicking enter you are verifying that you are old enough to consume alcohol.

Enter

Search

Main menu

Your cart is currently empty.
Shop now