Recombinant Rabbit monoclonal primary
Placental alkaline phosphatase Recombinant Rabbit Monoclonal Antibody [JM22-53] (ET1705-21)
Human placenta tissue, Hela.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
Placental alkaline phosphatase
Alkaline phosphatase antibody; Alkaline phosphatase placental antibody; Alkaline phosphatase placental type antibody; Alkaline phosphatase Regan isozyme antibody; ALP antibody; Alp1 antibody; ALPP antibody; FLJ61142 antibody; Germ-cell alkaline phosphatase antibody; nagao isozyme antibody; OTTHUMP00000164354 antibody; PALP antibody; Placental alkaline phosphatase 1 antibody; placental heat-stable alkaline phosphatase antibody; placental type antibody; PLAP antibody; PLAP-1 antibody; PLAP1 antibody; PPB1_HUMAN antibody
Belongs to the alkaline phosphatase family.
Detected in placenta (at protein level).
Alkaline phosphatases (AP) are glycosyl-phosphatidylinositol (GPI)-anchored, dimeric, Zn2+-metallated glycoproteins that catalyze the hydrolysis of phosphomonoesters into an inorganic phosphate and an alcohol. Placental alkaline phosphatase (also known as PLAP, ALPP, PALP, placental ALP-1 or Regan isozyme) is a 530 amino acid, tissue-specific AP that is expressed in the placenta, the serum of pregnant women and ectopically expressed in various cancers, including those of the ovary and testis. PLAP may assist in guiding migratory cells and transporting specific molecules, such as fatty acids and immunoglobulins, across the plasma membrane. The three tissue-specific APs identified in human, PLAP, germ cell AP (GCAP) and intestinal AP, are 90-98% homologous and their genes are clustered on chromosome 2q.