Recombinant Rabbit monoclonal primary
Pirh2 Recombinant Rabbit Monoclonal Antibody [JE55-39] (ET7111-16)
Synthetic peptide within n-terminal human pirh2.
293T cell lysates.
Store at +4Á¾ after thawing. Aliquot store at -20Á¾. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A affinity purified.
Androgen receptor N terminal interacting protein antibody; Androgen receptor N-terminal-interacting protein antibody; ARNIP antibody; CH-rich-interacting match with PLAG1 antibody; CHIMP antibody; E3 ubiquitin-protein ligase Pirh2 antibody; hARNIP antibody; hPirh2 antibody; p53 induced protein with a RING H2 domain antibody; p53-induced RING-H2 protein antibody; PIRH2E antibody; PIRH2F antibody; PRO1996 antibody; RCHY1 antibody; Ring finger and CHY zinc finger domain containing 1 E3 ubiquitin protein ligase antibody; RING finger and CHY zinc finger domain-containing protein 1 antibody; RING finger protein 199 antibody; RNF199 antibody; ZCHY antibody; ZFP 363 antibody; zinc finger CHY type antibody; Zinc finger protein 363 antibody; ZN363_HUMAN antibody; ZNF363 antibody
Nucleus, Nucleus speckle, Cytoplasm.
The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including tumor protein 53, histone deacetylase 1, and cyclin-dependent kinase inhibitor 1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.