Phospho-NF-kB p65 (S536) Recombinant Rabbit Monoclonal Antibody [PSH10-58] (HA723223)

UNIPROT #

Q04206

PROTEIN NAME

Phospho-NF-kB p65 (S536)

SYNONYMS

Avian reticuloendotheliosis viral (v rel) oncogene homolog A antibody;MGC131774 antibody;NF kappa B p65delta3 antibody;nfkappabp65 antibody;NFkB p65 antibody;NFKB3 antibody;Nuclear factor kappaB antibody;Nuclear Factor NF Kappa B p65 Subunit antibody;Nuclear factor NF-kappa-B p65 subunit antibody;Nuclear factor of kappa light polypeptide gene enhancer in B cells 3 antibody;Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 antibody;OTTHUMP00000233473 antibody;OTTHUMP00000233474 antibody;OTTHUMP00000233475 antibody;OTTHUMP00000233476 antibody;OTTHUMP00000233900 antibody;p65 antibody;p65 NF kappaB antibody;p65 NFkB antibody;relA antibody;TF65_HUMAN antibody;Transcription factor NFKB3 antibody;Transcription factor p65 antibody;v rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B cells 3 (p65)) antibody;V rel avian reticuloendotheliosis viral oncogene homolog A antibody;v rel reticuloendotheliosis viral oncogene homolog A (avian) antibody;V rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B cells 3, p65 antibody

SUBCELLULAR LOCATION

Nucleus, Cytoplasm.

FUNCTION

Transcription factor p65 also known as nuclear factor NF-kappa-B p65 subunit is a protein that in humans is encoded by the RELA gene. RELA, also known as p65, is a REL-associated protein involved in NF-κB heterodimer formation, nuclear translocation and activation. NF-κB is an essential transcription factor complex involved in all types of cellular processes, including cellular metabolism, chemotaxis, etc. Phosphorylation and acetylation of RELA are crucial post-translational modifications required for NF-κB activation. RELA has also been shown to modulate immune responses, and activation of RELA is positively associated with multiple types of cancer.