Phospho-Acetyl Coenzyme A Carboxylase (S79) Recombinant Rabbit Monoclonal Antibody [JE55-54] (HA721516)

UNIPROT #

Q13085

PROTEIN NAME

phospho-Acetyl Coenzyme A Carboxylase (S79)

SYNONYMS

ACAC antibody;ACACA antibody;ACACA_HUMAN antibody;ACACB antibody;ACC alpha antibody;ACC antibody;ACC beta antibody;ACC-alpha antibody;ACC1 antibody;ACC2 antibody;ACCA antibody;ACCB antibody;Acetyl CoA carboxylase 1 antibody;Acetyl CoA carboxylase 2 antibody;Acetyl CoA carboxylase alpha antibody;Acetyl CoA carboxylase beta antibody;Acetyl Coenzyme A carboxylase alpha antibody;Acetyl Coenzyme A carboxylase beta antibody;Biotin carboxylase antibody;COA1 antibody;COA2 antibody;HACC275 antibody;OTTHUMP00000164069 antibody;OTTHUMP00000164070 antibody;OTTHUMP00000164076 antibody;OTTHUMP00000240532 antibody

SUBCELLULAR LOCATION

Mitochondrion.

FUNCTION

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme (EC 6.4.1.2) that catalyzes the irreversible carboxylation of acetyl-CoA to produce malonyl-CoA through its two catalytic activities, biotin carboxylase (BC) and carboxyltransferase (CT). ACC is a multi-subunit enzyme in most prokaryotes and in the chloroplasts of most plants and algae, whereas it is a large, multi-domain enzyme in the cytoplasm of most eukaryotes. The most important function of ACC is to provide the malonyl-CoA substrate for the biosynthesis of fatty acids. The activity of ACC can be controlled at the transcriptional level as well as by small molecule modulators and covalent modification. The human genome contains the genes for two different ACCs —ACACA and ACACB.