Recombinant Rabbit monoclonal primary
Perilipin A Recombinant Rabbit Monoclonal Antibody [JM10-96] (ET1703-38)
Synthetic peptide within human perilipin a aa 470-510.
Human liver tissue lysates, MCF-7, HepG2, Hela.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A affinity purified.
Lipid droplet associated protein antibody; PERIA antibody; PERIB antibody; Perilipin A antibody; Perilipin antibody; Perilipin B antibody; PLIN antibody
Belongs to the perilipin family.
Detected in adipocytes from white adipose tissue (at protein level). Detected in visceral adipose tissue and mammary gland.
Major cAMP-dependent protein kinase-substrate in adipocytes, also dephosphorylated by PP1. When phosphorylated, may be maximally sensitive to HSL and when unphosphorylated, may play a role in the inhibition of lipolysis, by acting as a barrier in lipid droplet (By similarity).
Endoplasmic reticulum, Lipid droplet.
Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone-sensitive lipase (HSL). Its absence may result in leanness. Plays a role in unilocular lipid droplet formation by activating CIDEC. Their interaction promotes lipid droplet enlargement and directional net neutral lipid transfer. May modulate lipolysis and triglyceride levels.