PEPT1 Rabbit Polyclonal Antibody (HA500444)
Catalog# HA500444
Rabbit Polyclonal to PEPT1
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WB
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IHC-P
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IF-Tissue
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Human
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Mouse
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Rat
Lane 1: Liver (Mouse) Lysate at 40 ug
Lane 2: Liver (Rat) Lysate at 40 ug
Lane 3: Panc-1 (Human) Cell Lysate at 30 ug
Primary: Anti-SLC15A1 (bs-0689R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 80 kD
Observed band size: 83 kD
Specifications
Product Type
Rabbit polyclonal primary
Product Name
PEPT1 Rabbit Polyclonal Antibody (HA500444)
Immunogen
Klh conjugated synthetic peptide derived from human pept1: 101-200/714(chk)
Host
Rabbit
Conjugation
Unconjugated
Clonality
Polyclonal
RRID
APPLICATION DILUTION
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WB
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1:500-2000
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IHC-P
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1:100-500
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IF-tissue
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1:100-500
PROPERTIES
Form
Liquid
Storage Condition
Shipped at 4℃. Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration
1ug/ul
Purification
Protein A affinity purified.
Molecular Weight
79 kDa
Isotype
IgG
TARGET
UNIPROT #
PROTEIN NAME
PEPT1
SYNONYMS
+peptide cotransporter antibody;HPECT1 antibody;HPEPT1 antibody;Human peptide transporter (HPEPT1) mRNA complete cds antibody;Intestinal H antibody;Intestinal H(+)/peptide cotransporter antibody;Oligopeptide transporter antibody;Oligopeptide transporter small intestine isoform antibody;PEPT1 antibody;Peptide transporter 1 antibody;S15A1_HUMAN antibody;Slc15a1 antibody;small intestine isoform antibody;Solute carrier family 15 (oligopeptide transporter) member 1 antibody;Solute carrier family 15 member 1 antibody
SUBCELLULAR LOCATION
Membrane.
FUNCTION
Peptide transporter 1 (PepT 1) also known as solute carrier family 15 member 1 (SLC15A1) is a protein that in humans is encoded by SLC15A1 gene. PepT 1 is a solute carrier for oligopeptides. It functions in renal oligopeptide reabsorption and in the intestines in a proton dependent way, hence acting like a cotransporter. SLC15A1is localized to the brush border membrane of the intestinal epithelium and mediates the uptake of di- and tripeptides from the lumen into the enterocytes. This protein plays an important role in the uptake and digestion of dietary proteins. This protein also facilitates the absorption of numerous peptidomimetic drugs. Peptide transporter 1 functions in nutrient and drug transport have been studied using intestinal organoids.
CITATIONS
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Song Feifeng,et al
Peptide Transporter 1‐Mediated Dipeptide Transport Promotes Hepatocellular Carcinoma Metastasis by Activating MAP4K4/G3BP2 Signaling Axis
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WB
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IHC
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Human
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Citation
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