PE Conjugated Human CD3 Recombinant Mouse Monoclonal Antibody [PSH04-92] (HA600117F)

UNIPROT #

P07766

PROTEIN NAME

Human CD3

SYNONYMS

CD3 epsilon antibody;CD3e antibody;CD3e antigen antibody;CD3e antigen epsilon polypeptide (TiT3 complex) antibody;CD3E antigen epsilon polypeptide antibody;CD3E antigen, epsilon subunit antibody;CD3e molecule epsilon antibody;CD3e molecule, epsilon (CD3 TCR complex) antibody;CD3e molecule, epsilon (CD3-TCR complex) antibody;CD3E_HUMAN antibody;IMD18 antibody;T cell antigen receptor complex epsilon subunit of T3 antibody;T cell surface antigen T3/Leu 4 epsilon chain antibody;T cell surface glycoprotein CD3 epsilon chain antibody;T-cell surface antigen T3/Leu-4 epsilon chain antibody;T-cell surface glycoprotein CD3 epsilon chain antibody;T3E antibody;TCRE antibody

SUBCELLULAR LOCATION

Cell membrane.

FUNCTION

CD3 (cluster of differentiation 3) is a protein complex and T cell co-receptor that is involved in activating both the cytotoxic T cell (CD8+ naive T cells) and T helper cells (CD4+ naive T cells). It is composed of four distinct chains. In mammals, the complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. These chains associate with the T-cell receptor (TCR) and the CD3-zeta (ζ-chain) to generate an activation signal in T lymphocytes. The TCR, CD3-zeta, and the other CD3 molecules together constitute the TCR complex.