Recombinant production enables lot-to-lot consistency and is animal-cruelty-free
Western blot analysis of Pax2 on human kidney tissue lysates with Rabbit anti-Pax2 antibody (ET1701-23) at 1/500 dilution.
Lysates/proteins at 20 µg/Lane.
Predicted band size: 45 kDa
Observed band size: 45 kDa
Exposure time: 2 minutes;
10% SDS-PAGE gel.
Proteins were transferred to a PVDF membrane and blocked with 5% NFDM/TBST for 1 hour at room temperature. The primary antibody (ET1701-23) at 1/500 dilution was used in 5% NFDM/TBST at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody (HA1001) at 1:300,000 dilution was used for 1 hour at room temperature.
FSGS7 antibody;Paired box 2 antibody;Paired box gene 2 antibody;paired box homeotic gene 2 antibody;paired box protein 2 antibody;Paired box protein Pax 2 antibody;Paired box protein Pax-2 antibody;Paired box protein Pax2 antibody;PAPRS antibody;Pax 2 antibody
Expressed in primitive cells of the kidney, ureter, eye, ear and central nervous system.
Mainly in fetal kidney and juvenile nephrogenic rests.
Paired box gene 2, also known as PAX2, is a protein which in humans is encoded by the PAX2 gene. The Pax Genes, or Paired-Box Containing Genes, play important roles in the development and proliferation of multiple cell lines, development of organs, and development and organization of the central nervous system. The transcription factor gene Pax2 is important in the regionalized embryological development of the central nervous system. In mammals, the brain is developed in three regions: the forebrain, midbrain, and the hindbrain. Concentration gradients of fibroblast growth factor 8 (FGF8) and Wingless-Type MMTV Integration Site Family, Member 1 (Wnt1) control expression of Pax2 during development of the Mesencephalon, or midbrain. The Pax2 gene encodes for the transcription factor which appears to be essential in the organization of the midbrain and hindbrain regions, and at the earliest can be detected on either side of the sulcus limitans, which separates motor and sensory nerve nuclei. PAX2 mutations can be responsible for renal hypoplasia, either isolated or associated with various ophthalmologic manifestations ranging from retinal coloboma to microphthalmia.
Just like the interactions between antigens and antibodies, the higher the affinity between you and us the better.