Applications
-
WB
-
IHC-P
REACTIVITY
-
Human
-
Mouse
-
Rat
SPECIFICATIONS
Product Type
Rabbit polyclonal primary
Product Name
P2X3 Rabbit Polyclonal Antibody (ER1902-88)
Immunogen
Synthetic peptide within mouse p2x3 aa 348-397 / 397.
Host
Rabbit
Positive Control
Mouse testis tissue lysates, rat spinal cord tissue, mouse brain tissue.
Conjugation
Unconjugated
Clonality
Polyclonal
PROPERTIES
Form
Liquid
Storage Condition
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 ug/ul
PURIFICATION
Peptide affinity purified.
MOLECULAR WEIGHT
Predicted band size: 44 kDa
Isotype
IgG
APPLICATION DILUTION
-
WB:1:500-1:1,000
-
IHC-P:1:50-1:200
TARGET
UNIPROT #
PROTEIN NAME
P2X3
SYNONYMS
ATP receptor antibody; MGC129956 antibody; P2rx3 antibody; P2RX3_HUMAN antibody; P2X purinoceptor 3 antibody; P2X receptor subunit 3 antibody; P2X3 antibody; Purinergic receptor antibody; Purinergic receptor P2X ligand gated ion channel 3 antibody; Purinergic receptor P2X3 antibody; Purinoceptor P2X3 antibody
SEQUENCE SIMILARITIES
Belongs to the P2X receptor family.
SUBCELLULAR LOCATION
Cell membrane.
FUNCTION
This gene encodes a member of the P2X purinergic receptor (purinoceptor) gene family which includes seven members (P2RX1 - P2RX7). P2X purinoceptors are a family of cation-permeable, ligand-gated ion channels that open in response to the binding of extracellular adenosine 5'-triphosphate (ATP). The encoded protein is a subunit of the trimeric P2X3 receptor ion channel which is expressed by sensory or autonomic neurons. A deficiency of the orthologous protein in mice is associated with reduced pain-related behavior and urinary bladder hyporeflexia.