P2X3 Rabbit Polyclonal Antibody (ER1902-88)

UNIPROT #

P56373

PROTEIN NAME

P2X3

SYNONYMS

ATP receptor antibody;MGC129956 antibody;P2rx3 antibody;P2RX3_HUMAN antibody;P2X purinoceptor 3 antibody;P2X receptor subunit 3 antibody;P2X3 antibody;Purinergic receptor antibody;Purinergic receptor P2X ligand gated ion channel 3 antibody;Purinergic receptor P2X3 antibody;Purinoceptor P2X3 antibody

SEQUENCE SIMILARITIES

Belongs to the P2X receptor family.

SUBCELLULAR LOCATION

Cell membrane.

FUNCTION

This gene encodes a member of the P2X purinergic receptor (purinoceptor) gene family which includes seven members (P2RX1 - P2RX7). P2X purinoceptors are a family of cation-permeable, ligand-gated ion channels that open in response to the binding of extracellular adenosine 5'-triphosphate (ATP). The encoded protein is a subunit of the trimeric P2X3 receptor ion channel which is expressed by sensory or autonomic neurons. A deficiency of the orthologous protein in mice is associated with reduced pain-related behavior and urinary bladder hyporeflexia.