Lane 1: Mouse brain tissue lysate
Lane 2: Mouse cerebellum tissue lysate
Lane 3: SH-SY5Y cell lysate
Rabbit polyclonal primary
P2RX1 Rabbit Polyclonal Antibody (ER1901-53)
Synthetic peptide within human p2x1 aa 252-301 / 399.
Mouse brain tissue lysate, mouse cerebellum tissue lysate, SH-SY5Y cell lysate, SHG-44, SiHa, SKOV-3, rat brain tissue, human prostate carcinoma tissue, human kidney carcinoma tissue, mouse brain tissue, mouse cerebellum tissue, THP-1.
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Peptide affinity purified.
ATP receptor antibody; H.sapiens mRNA for ATP receptor antibody; P2 RX1 antibody; P2rx1 antibody; P2RX1 protein antibody; P2RX1_HUMAN antibody; P2X purinoceptor 1 antibody; P2X receptor subunit 1 antibody; P2X1 antibody; P2X1 receptor antibody; Purinergic receptor antibody; Purinergic receptor P2X ligand gated ion channel 1 antibody; Purinergic receptor P2X1 antibody
Belongs to the P2X receptor family.
P2X purinoceptor 1 is a protein that in humans is encoded by the P2RX1 gene. The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Expressed in smooth muscle and platelets. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. It is possible that the development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill.