OTC/Ornithine Carbamoyltransferase Rabbit Polyclonal Antibody (HA500048)

UNIPROT #

P00480

PROTEIN NAME

OTC/Ornithine Carbamoyltransferase

SYNONYMS

EC 2.1.3.3 antibody;MGC129967 antibody;MGC129968 antibody;MGC138856 antibody;OCTD antibody;Ornithine Carbamoyltransferase antibody;Ornithine carbamoyltransferase mitochondrial antibody;Ornithine carbamoyltransferase, mitochondrial antibody;Ornithine transcarbamylase antibody;Otc antibody;OTC_HUMAN antibody;OTCase antibody

SUBCELLULAR LOCATION

Mitochondrion.

FUNCTION

Ornithine transcarbamylase (OTC) (also called ornithine carbamoyltransferase) is an enzyme (EC 2.1.3.3) that catalyzes the reaction between carbamoyl phosphate (CP) and ornithine (Orn) to form citrulline (Cit) and phosphate (Pi). There are two classes of OTC anabolic and catabolic. This article focuses on anabolic OTC. Anabolic OTC facilitates the sixth step in the biosynthesis of the amino acid arginine in prokaryotes.[5] In contrast, mammalian OTC plays an essential role in the urea cycle whose purpose is to capture toxic ammonia and transform it into less toxic urea nitrogen source for excretion.